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However, during the course of those experiments, we additionally noticed that, unlike the enterocyte driver mex-Gal4, two routinely used esg-Gal4 intestinal progenitor drivers are additionally expressed in a few cells within the ovary (see Writer response picture 2 , images by Bruno Hudry and Jake Jacobson, Miguel-Aliaga lab).
Additional evidence is that other genes that cause myofibrillar myopathies when mutated, are Desm, and chaperones DnajB6, HspB8, Cryab and Bag3 which suggest these chaperones are crucial to stabilizing the folded state of Flnc ( Kley et al., 2016 ). We also famous Bag3, which also co-localizes in stress granules, as one among our proteins that turn out to be extra insoluble in at the least 3 stresses.